Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM202034'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM202034 (1-(6-(2-(6-chloro-4-(dimethylamino)quinazolin-2-yl...) Show SMILES CN(C)c1nc(CCc2cccc(n2)N2CCC(O)C2)nc2ccc(Cl)cc12 Show InChI InChI=1S/C21H24ClN5O/c1-26(2)21-17-12-14(22)6-8-18(17)24-19(25-21)9-7-15-4-3-5-20(23-15)27-11-10-16(28)13-27/h3-6,8,12,16,28H,7,9-11,13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	25
Hoffmann-La Roche, Inc. US Patent					Assay Description The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 .mu.l contained 20 mM HEPES pH=7.5/10 mM M...				US Patent US9540384 (2017) BindingDB Entry DOI: 10.7270/Q2HT2MG1
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