Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM317170'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM317170 (2,3-Dimethyl-6-((1-methyl-3-(pyrrolidin-1-yl)-1H-1...) Show SMILES Cc1nc2ccc(SCc3nc(nn3C)N3CCCC3)nn2c1C Show InChI InChI=1S/C16H21N7S/c1-11-12(2)23-13(17-11)6-7-15(19-23)24-10-14-18-16(20-21(14)3)22-8-4-5-9-22/h6-7H,4-5,8-10H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	568	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...				US Patent US9617271 (2017) BindingDB Entry DOI: 10.7270/Q2N58PFC
					More data for this Ligand-Target Pair