Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM347640'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM347640 (4-Methyl-2-((4-(1-methyl-4-(pyridin-4-yl)-1H-pyraz...) Show SMILES Cc1ccnc(c1)C#Cc1ccc(cc1)-c1nn(C)cc1-c1ccncc1 Show InChI InChI=1S/C23H18N4/c1-17-9-14-25-21(15-17)8-5-18-3-6-20(7-4-18)23-22(16-27(2)26-23)19-10-12-24-13-11-19/h3-4,6-7,9-16H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
ABBVIE INC.; ABBVIE DEUTSCHLAND GMBH & CO. KG US Patent					Assay Description The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...				US Patent US9790203 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6VD4
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