Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM50019128'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50019128 (CHEMBL3288423) Show SMILES COc1ccnc2n(c(CCn3c4nccnc4n(C)c3=O)nc12)-c1ccccc1 Show InChI InChI=1S/C21H19N7O2/c1-26-19-20(24-12-11-23-19)27(21(26)29)13-9-16-25-17-15(30-2)8-10-22-18(17)28(16)14-6-4-3-5-7-14/h3-8,10-12H,9,13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	111	n/a	n/a	n/a	n/a	n/a	n/a
Yamanouchi Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE10A expressed in Sf9 insect cell system assessed as inhibition of cAMP hydrolysis preincubated for 30 mins before ...				Bioorg Med Chem 22: 3515-26 (2014) Article DOI: 10.1016/j.bmc.2014.04.023 BindingDB Entry DOI: 10.7270/Q2RN39D7
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