Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM50348363'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Mus musculus)	BDBM50348363 (CHEMBL1800826) Show SMILES COc1cc(\C=N\NC(=O)CSc2cc(C)nc3ccccc23)ccc1C(F)(F)F Show InChI InChI=1S/C21H18F3N3O2S/c1-13-9-19(15-5-3-4-6-17(15)26-13)30-12-20(28)27-25-11-14-7-8-16(21(22,23)24)18(10-14)29-2/h3-11H,12H2,1-2H3,(H,27,28)/b25-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Omeros Corp. Curated by ChEMBL					Assay Description Inhibition of mouse PDE10A assessed as inhibition of hydrolysis of [3H]cGMP to [3H]GMP after 20 mins by scintillation counting				Bioorg Med Chem Lett 21: 4155-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.100 BindingDB Entry DOI: 10.7270/Q2CJ8FRT
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