Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM50351900'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50351900 (CHEMBL1821778) Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OCCF)cc23)cc1C Show InChI InChI=1S/C21H22FNO3/c1-14-10-15(4-5-19(14)24-2)11-18-17-13-21(26-9-7-22)20(25-3)12-16(17)6-8-23-18/h4-6,8,10,12-13H,7,9,11H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	244	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE10A assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assay				Eur J Med Chem 46: 3986-95 (2011) Article DOI: 10.1016/j.ejmech.2011.05.072 BindingDB Entry DOI: 10.7270/Q279452C
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