Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM50390822'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50390822 (CHEMBL2070659) Show SMILES COc1cc(F)cc2c1nnc1c(C)nc(-c3cccc(F)c3C)n21 Show InChI InChI=1S/C18H14F2N4O/c1-9-12(5-4-6-13(9)20)18-21-10(2)17-23-22-16-14(24(17)18)7-11(19)8-15(16)25-3/h4-8H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.55	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis				Bioorg Med Chem Lett 22: 5876-84 (2012) Article DOI: 10.1016/j.bmcl.2012.07.076 BindingDB Entry DOI: 10.7270/Q2FB5413
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50390822 (CHEMBL2070659) Show SMILES COc1cc(F)cc2c1nnc1c(C)nc(-c3cccc(F)c3C)n21 Show InChI InChI=1S/C18H14F2N4O/c1-9-12(5-4-6-13(9)20)18-21-10(2)17-23-22-16-14(24(17)18)7-11(19)8-15(16)25-3/h4-8H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant PDE10A1 expressed in baculovirus infected SF21 cells using [3H]cAMP as substrate after 30 mins by liquid scintillation coun...				J Med Chem 55: 7299-331 (2012) Article DOI: 10.1021/jm3004976 BindingDB Entry DOI: 10.7270/Q2C24XJK
					More data for this Ligand-Target Pair