Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM50401318'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50401318 (CHEMBL2205223) Show SMILES CN(CCc1ccccn1)c1nc(nc2CCN(Cc12)C(=O)Nc1ccccc1)-c1cccc(Br)c1 Show InChI InChI=1S/C28H27BrN6O/c1-34(16-13-22-10-5-6-15-30-22)27-24-19-35(28(36)31-23-11-3-2-4-12-23)17-14-25(24)32-26(33-27)20-8-7-9-21(29)18-20/h2-12,15,18H,13-14,16-17,19H2,1H3,(H,31,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	991	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE10A				Bioorg Med Chem Lett 22: 5903-8 (2012) Article DOI: 10.1016/j.bmcl.2012.07.072 BindingDB Entry DOI: 10.7270/Q23J3F3X
					More data for this Ligand-Target Pair