Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM50401319'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50401319 (CHEMBL2205218) Show SMILES CN(CCc1ccccn1)c1nc(nc2CCN(Cc12)C(=O)Nc1ccccc1)-c1ccccc1 Show InChI InChI=1S/C28H28N6O/c1-33(18-15-22-12-8-9-17-29-22)27-24-20-34(28(35)30-23-13-6-3-7-14-23)19-16-25(24)31-26(32-27)21-10-4-2-5-11-21/h2-14,17H,15-16,18-20H2,1H3,(H,30,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE10A				Bioorg Med Chem Lett 22: 5903-8 (2012) Article DOI: 10.1016/j.bmcl.2012.07.072 BindingDB Entry DOI: 10.7270/Q23J3F3X
					More data for this Ligand-Target Pair