Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [440-779]' and Ligand = 'BDBM197741'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [440-779] (Homo sapiens (Human))	BDBM197741 (US9216986, 2-[2-(6-Fluoro-quinolin-2-yl)-ethyl]-5-...) Show SMILES Cc1ccc(O)c2nc(CCc3ccc4cc(F)ccc4n3)nn12 Show InChI InChI=1S/C18H15FN4O/c1-11-2-8-16(24)18-21-17(22-23(11)18)9-6-14-5-3-12-10-13(19)4-7-15(12)20-14/h2-5,7-8,10,24H,6,9H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9216986 (2015) BindingDB Entry DOI: 10.7270/Q2Z31XG5
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