Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [440-779]' and Ligand = 'BDBM197772'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [440-779] (Homo sapiens (Human))	BDBM197772 (US9216986, 7-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-...) Show SMILES Cc1cnc(C)c2nc(CCc3ccc4cc5OCCOc5cc4n3)nn12 Show InChI InChI=1S/C20H19N5O2/c1-12-11-21-13(2)20-23-19(24-25(12)20)6-5-15-4-3-14-9-17-18(10-16(14)22-15)27-8-7-26-17/h3-4,9-11H,5-8H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9216986 (2015) BindingDB Entry DOI: 10.7270/Q2Z31XG5
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