Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-dependent protein kinase catalytic subunit alpha' and Ligand = 'BDBM3228'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-dependent protein kinase catalytic subunit alpha (Bos taurus (bovine))	BDBM3228 ((3R,4R)-4-[(4-hydroxybenzene)amido]pyrrolidin-3-yl...) Show SMILES Oc1ccc(cc1)C(=O)N[C@@H]1CNC[C@H]1OC(=O)c1cc(O)c(C(=O)c2c(O)ccc3ccccc23)c(O)c1 |r| Show InChI InChI=1S/C29H24N2O8/c32-18-8-5-16(6-9-18)28(37)31-20-13-30-14-24(20)39-29(38)17-11-22(34)26(23(35)12-17)27(36)25-19-4-2-1-3-15(19)7-10-21(25)33/h1-12,20,24,30,32-35H,13-14H2,(H,31,37)/t20-,24-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Sphinx Laboratories					Assay Description The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.				J Med Chem 45: 2624-43 (2002) Article DOI: 10.1021/jm020018f BindingDB Entry DOI: 10.7270/Q2BG2M50
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