Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-dependent protein kinase catalytic subunit alpha' and Ligand = 'BDBM4100'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-dependent protein kinase catalytic subunit alpha (Bos taurus (bovine))	BDBM4100 (4-[(1,2,6,7-tetrahydroxy-9H-carbazol-9-yl)methyl]b...) Show SMILES Oc1cc2n(Cc3ccc(cc3)C#N)c3c(O)c(O)ccc3c2cc1O Show InChI InChI=1S/C20H14N2O4/c21-9-11-1-3-12(4-2-11)10-22-15-8-18(25)17(24)7-14(15)13-5-6-16(23)20(26)19(13)22/h1-8,23-26H,10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.75E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...				J Med Chem 37: 2224-31 (1994) Article DOI: 10.1021/jm00040a015 BindingDB Entry DOI: 10.7270/Q27M0648
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