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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-dependent protein kinase catalytic subunit gamma' and Ligand = 'BDBM50228845'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-dependent protein kinase catalytic subunit gamma


(Homo sapiens (Human))		BDBM50228845
PNG
(CHEMBL410778)
Show SMILES [#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]S(=O)(=O)c1ccc(-[#7](-[#6])-[#6])c2ccccc12)-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](-[#8])=O
Show InChI InChI=1S/C45H76N20O10S/c1-24(59-37(68)26(3)64-76(74,75)34-19-18-33(65(4)5)27-12-6-7-13-28(27)34)35(66)58-25(2)36(67)60-29(14-8-20-54-42(46)47)38(69)61-30(15-9-21-55-43(48)49)39(70)62-31(16-10-22-56-44(50)51)40(71)63-32(41(72)73)17-11-23-57-45(52)53/h6-7,12-13,18-19,24-26,29-32,64H,8-11,14-17,20-23H2,1-5H3,(H,58,66)(H,59,68)(H,60,67)(H,61,69)(H,62,70)(H,63,71)(H,72,73)(H4,46,47,54)(H4,48,49,55)(H4,50,51,56)(H4,52,53,57)/t24-,25-,26-,29-,30-,31-,32-/m0/s1
KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>7.50E+4n/an/an/an/an/an/a



URA CNRS 1309

Curated by ChEMBL


Assay Description
Inhibition of cAMP-dependent protein kinase (PKA).

J Med Chem 34: 73-8 (1991)


BindingDB Entry DOI: 10.7270/Q2J38VS9
More data for this
Ligand-Target Pair