Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D' and Ligand = 'BDBM50045026'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50045026 (2-(2-Propoxy-phenyl)-3H-imidazo[4,5-b]pyridine | C...) Show SMILES CCCOc1ccccc1-c1nc2ncccc2[nH]1 Show InChI InChI=1S/C15H15N3O/c1-2-10-19-13-8-4-3-6-11(13)14-17-12-7-5-9-16-15(12)18-14/h3-9H,2,10H2,1H3,(H,16,17,18)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibition of PDE-IV isolated from guinea pig ventricle.				J Med Chem 36: 1387-92 (1993) BindingDB Entry DOI: 10.7270/Q2JW8FHP
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