Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D' and Ligand = 'BDBM50215960'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50215960 (CHEMBL336848) Show SMILES COc1ccc(cc1OC1CCCC1)C1(CC#N)CCN(C(=O)OC(C)(C)C)C1=O Show InChI InChI=1S/C23H30N2O5/c1-22(2,3)30-21(27)25-14-12-23(11-13-24,20(25)26)16-9-10-18(28-4)19(15-16)29-17-7-5-6-8-17/h9-10,15,17H,5-8,11-12,14H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	476	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rh£ne-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description Affinity for phosphodiesterase (PDE IV) in guinea pig brain membrane using [3H]rolipram displacement.				Bioorg Med Chem Lett 8: 399-404 (1998) BindingDB Entry DOI: 10.7270/Q2222WZ0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50215960 (CHEMBL336848) Show SMILES COc1ccc(cc1OC1CCCC1)C1(CC#N)CCN(C(=O)OC(C)(C)C)C1=O Show InChI InChI=1S/C23H30N2O5/c1-22(2,3)30-21(27)25-14-12-23(11-13-24,20(25)26)16-9-10-18(28-4)19(15-16)29-17-7-5-6-8-17/h9-10,15,17H,5-8,11-12,14H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Rh£ne-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description In vitro inhibition of phosphodiesterase (PDE IV) from guinea pig macrophages.				Bioorg Med Chem Lett 8: 399-404 (1998) BindingDB Entry DOI: 10.7270/Q2222WZ0
					More data for this Ligand-Target Pair