Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D' and Ligand = 'BDBM50218419'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50218419 (CHEMBL91952) Show SMILES CC(C)n1nc2c(cn(Cc3ccccc3)c3ccccc23)c1=O Show InChI InChI=1S/C20H19N3O/c1-14(2)23-20(24)17-13-22(12-15-8-4-3-5-9-15)18-11-7-6-10-16(18)19(17)21-23/h3-11,13-14H,12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibitory potency against guinea pig ventricular phosphodiesterase 4				Bioorg Med Chem Lett 10: 2661-4 (2000) BindingDB Entry DOI: 10.7270/Q20Z75FT
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (RAT-Rattus norvegicus)	BDBM50218419 (CHEMBL91952) Show SMILES CC(C)n1nc2c(cn(Cc3ccccc3)c3ccccc23)c1=O Show InChI InChI=1S/C20H19N3O/c1-14(2)23-20(24)17-13-22(12-15-8-4-3-5-9-15)18-11-7-6-10-16(18)19(17)21-23/h3-11,13-14H,12H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Displacement of [3H]rolipram from high affinity binding site (HARBS) in rat brain membrane.				Bioorg Med Chem Lett 10: 2661-4 (2000) BindingDB Entry DOI: 10.7270/Q20Z75FT
					More data for this Ligand-Target Pair