Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D' and Ligand = 'BDBM50219415'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50219415 (CHEMBL83872) Show SMILES COc1ccc2C(Cc3c(Cl)cncc3Cl)=NN(Cc2c1)C(=O)c1ccccc1 |c:16| Show InChI InChI=1S/C22H17Cl2N3O2/c1-29-16-7-8-17-15(9-16)13-27(22(28)14-5-3-2-4-6-14)26-21(17)10-18-19(23)11-25-12-20(18)24/h2-9,11-12H,10,13H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research Curated by ChEMBL					Assay Description In vitro inhibitory concentration against phosphodiesterase 4.				Bioorg Med Chem Lett 13: 2473-9 (2003) BindingDB Entry DOI: 10.7270/Q24F1SXB
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50219415 (CHEMBL83872) Show SMILES COc1ccc2C(Cc3c(Cl)cncc3Cl)=NN(Cc2c1)C(=O)c1ccccc1 |c:16| Show InChI InChI=1S/C22H17Cl2N3O2/c1-29-16-7-8-17-15(9-16)13-27(22(28)14-5-3-2-4-6-14)26-21(17)10-18-19(23)11-25-12-20(18)24/h2-9,11-12H,10,13H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Zambon Group Curated by ChEMBL					Assay Description Inhibition of human neutrophil phosphodiesterase type IV (PDE4)				Bioorg Med Chem Lett 12: 5-8 (2002) BindingDB Entry DOI: 10.7270/Q2SB47Z5
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50219415 (CHEMBL83872) Show SMILES COc1ccc2C(Cc3c(Cl)cncc3Cl)=NN(Cc2c1)C(=O)c1ccccc1 |c:16| Show InChI InChI=1S/C22H17Cl2N3O2/c1-29-16-7-8-17-15(9-16)13-27(22(28)14-5-3-2-4-6-14)26-21(17)10-18-19(23)11-25-12-20(18)24/h2-9,11-12H,10,13H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research Curated by ChEMBL					Assay Description Inhibitory concentration against phosphodiesterase 4.				Bioorg Med Chem Lett 13: 2473-9 (2003) BindingDB Entry DOI: 10.7270/Q24F1SXB
					More data for this Ligand-Target Pair