Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D' and Ligand = 'BDBM50226863'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50226863 (CHEMBL280851) Show SMILES CCc1[nH]c(O)nc1C(=O)c1ccc(cc1)-c1ncc[nH]1 Show InChI InChI=1S/C15H14N4O2/c1-2-11-12(19-15(21)18-11)13(20)9-3-5-10(6-4-9)14-16-7-8-17-14/h3-8H,2H2,1H3,(H,16,17)(H2,18,19,21)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of canine cardiac cAMP phosphodiesterase (cAMP-PDE)				J Med Chem 30: 1342-7 (1987) BindingDB Entry DOI: 10.7270/Q2DV1N40
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