Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D' and Ligand = 'BDBM50471675'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50471675 (CHEMBL307678) Show SMILES CCc1nn(C2CCCC2)c2c1CCN(C2=O)c1cccc(OC)c1 Show InChI InChI=1S/C20H25N3O2/c1-3-18-17-11-12-22(15-9-6-10-16(13-15)25-2)20(24)19(17)23(21-18)14-7-4-5-8-14/h6,9-10,13-14H,3-5,7-8,11-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity on human eosinophil phosphodiesterase 4.				J Med Chem 41: 2268-77 (1998) Article DOI: 10.1021/jm9800090 BindingDB Entry DOI: 10.7270/Q27S7RH6
					More data for this Ligand-Target Pair