Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D' and Ligand = 'BDBM50471841'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50471841 (CHEMBL334988) Show SMILES C(Nc1nc(nc2ccsc12)-c1ccncc1)c1ccccc1 Show InChI InChI=1S/C18H14N4S/c1-2-4-13(5-3-1)12-20-18-16-15(8-11-23-16)21-17(22-18)14-6-9-19-10-7-14/h1-11H,12H2,(H,20,21,22)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissue				J Med Chem 41: 4021-35 (1998) Article DOI: 10.1021/jm981012m BindingDB Entry DOI: 10.7270/Q2TM7DV3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50471841 (CHEMBL334988) Show SMILES C(Nc1nc(nc2ccsc12)-c1ccncc1)c1ccccc1 Show InChI InChI=1S/C18H14N4S/c1-2-4-13(5-3-1)12-20-18-16-15(8-11-23-16)21-17(22-18)14-6-9-19-10-7-14/h1-11H,12H2,(H,20,21,22)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophils				J Med Chem 41: 4021-35 (1998) Article DOI: 10.1021/jm981012m BindingDB Entry DOI: 10.7270/Q2TM7DV3
					More data for this Ligand-Target Pair