Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D' and Ligand = 'BDBM50473355'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50473355 (CHEMBL430831) Show SMILES COc1ccc(cc1OC(F)F)C1=NN(C2CCCCCC2)C(=O)C2CC=CCC12 |c:28,t:13| Show InChI InChI=1S/C23H28F2N2O3/c1-29-19-13-12-15(14-20(19)30-23(24)25)21-17-10-6-7-11-18(17)22(28)27(26-21)16-8-4-2-3-5-9-16/h6-7,12-14,16-18,23H,2-5,8-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Inhibition of phosphodiesterase 4 (PDE4) in human neutrophils				J Med Chem 44: 2523-35 (2001) Article DOI: 10.1021/jm010838c BindingDB Entry DOI: 10.7270/Q23N2644
					More data for this Ligand-Target Pair