Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D' and Ligand = 'BDBM50473696'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50473696 (CHEMBL85056) Show SMILES COc1ccc(cc1OC)C1=NN(Cc2ccc(O)cc2)C(=O)C2CCCCC12 |t:11| Show InChI InChI=1S/C23H26N2O4/c1-28-20-12-9-16(13-21(20)29-2)22-18-5-3-4-6-19(18)23(27)25(24-22)14-15-7-10-17(26)11-8-15/h7-13,18-19,26H,3-6,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Inhibitory concentration against phosphodiesterase 4 (PDE4) in cytosol of human neutrophils				J Med Chem 45: 2520-5 (2002) Article DOI: 10.1021/jm0110340 BindingDB Entry DOI: 10.7270/Q2862K56
					More data for this Ligand-Target Pair