Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D' and Ligand = 'BDBM50473705'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50473705 (CHEMBL85307) Show SMILES COc1ccc(cc1OC)C1=NN(CCCCCCN)C(=O)C2CCCCC12 |t:11| Show InChI InChI=1S/C22H33N3O3/c1-27-19-12-11-16(15-20(19)28-2)21-17-9-5-6-10-18(17)22(26)25(24-21)14-8-4-3-7-13-23/h11-12,15,17-18H,3-10,13-14,23H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Inhibitory concentration against phosphodiesterase 4 (PDE4) in cytosol of human neutrophils				J Med Chem 45: 2520-5 (2002) Article DOI: 10.1021/jm0110340 BindingDB Entry DOI: 10.7270/Q2862K56
					More data for this Ligand-Target Pair