Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D' and Ligand = 'BDBM50473732'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50473732 (CHEMBL83197) Show SMILES COc1ccc(cc1OC)C1=NN(CCCOc2ccccc2)C(=O)C2CCCCC12 |t:11| Show InChI InChI=1S/C25H30N2O4/c1-29-22-14-13-18(17-23(22)30-2)24-20-11-6-7-12-21(20)25(28)27(26-24)15-8-16-31-19-9-4-3-5-10-19/h3-5,9-10,13-14,17,20-21H,6-8,11-12,15-16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Inhibitory concentration against phosphodiesterase 4 (PDE4) in cytosol of human neutrophils				J Med Chem 45: 2520-5 (2002) Article DOI: 10.1021/jm0110340 BindingDB Entry DOI: 10.7270/Q2862K56
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