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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A' and Ligand = 'BDBM130933'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A


(Homo sapiens (Human))
BDBM130933
PNG
(US8829190, 111)
Show SMILES CCCNC(=O)C1(CC1)c1nc2c(OC)ccc(C(=O)Cc3c(Cl)cncc3Cl)n2n1
Show InChI InChI=1S/C21H21Cl2N5O3/c1-3-8-25-20(30)21(6-7-21)19-26-18-17(31-2)5-4-15(28(18)27-19)16(29)9-12-13(22)10-24-11-14(12)23/h4-5,10-11H,3,6-9H2,1-2H3,(H,25,30)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.300n/an/an/an/an/an/a



Leo Pharma A/S

US Patent


Assay Description
Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...


US Patent US8829190 (2014)

More data for this
Ligand-Target Pair