Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A' and Ligand = 'BDBM30045'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM30045 (triazolothiadiazine, 39) Show SMILES COc1ccc(cc1OC1CCCC1)C1=Nn2c(SC1)nnc2-c1ccccc1C(F)(F)F |t:16| Show InChI InChI=1S/C23H21F3N4O2S/c1-31-19-11-10-14(12-20(19)32-15-6-2-3-7-15)18-13-33-22-28-27-21(30(22)29-18)16-8-4-5-9-17(16)23(24,25)26/h4-5,8-12,15H,2-3,6-7,13H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	7.2	22
National Human Genome Research Institute					Assay Description Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...				Bioorg Med Chem Lett 19: 3686-92 (2009) Article DOI: 10.1016/j.bmcl.2009.01.057 BindingDB Entry DOI: 10.7270/Q2W37TNT
					More data for this Ligand-Target Pair