Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A' and Ligand = 'BDBM50125075'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50125075 (4-[2-[3,4-di(difluoromethoxy)phenyl]-2-(6-tetrahyd...) Show SMILES [O-][n+]1ccc(CC(c2ccc(nc2)N2CCCC2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1 Show InChI InChI=1S/C24H23F4N3O3/c25-23(26)33-20-5-3-17(14-21(20)34-24(27)28)19(13-16-7-11-31(32)12-8-16)18-4-6-22(29-15-18)30-9-1-2-10-30/h3-8,11-12,14-15,19,23-24H,1-2,9-10,13H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in...				Bioorg Med Chem Lett 13: 741-4 (2003) BindingDB Entry DOI: 10.7270/Q2PG1R3G
					More data for this Ligand-Target Pair