Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A' and Ligand = 'BDBM50328107'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50328107 (CHEMBL1257655 | N-(2-Methoxybenzyl)-2,2-dimethyl-5...) Show SMILES COc1ccccc1CNc1ncnc2c1sc1nc(N3CCOCC3)c3COC(C)(C)Cc3c21 Show InChI InChI=1S/C26H29N5O3S/c1-26(2)12-17-18(14-34-26)24(31-8-10-33-11-9-31)30-25-20(17)21-22(35-25)23(29-15-28-21)27-13-16-6-4-5-7-19(16)32-3/h4-7,15H,8-14H2,1-3H3,(H,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of PDE4A4 expressed in yeast				J Med Chem 53: 6912-22 (2010) Article DOI: 10.1021/jm100524j BindingDB Entry DOI: 10.7270/Q2J966K2
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