Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM332071'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM332071 (US10189854, Compound 23 | [1-[5-[2-Fluoro-5-(trifl...) Show SMILES Fc1ccc(cc1-c1cnc(nc1)N1CC2(CC2)c2ccc(cc12)C(=O)N1CCOCC1)C(F)(F)F Show InChI InChI=1S/C26H22F4N4O2/c27-21-4-2-18(26(28,29)30)12-19(21)17-13-31-24(32-14-17)34-15-25(5-6-25)20-3-1-16(11-22(20)34)23(35)33-7-9-36-10-8-33/h1-4,11-14H,5-10,15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GRUENENTHAL GMBH US Patent					Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...				US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4
					More data for this Ligand-Target Pair