Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM332095'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM332095 (US10189854, Compound 49 | [1-(5-Phenyl-pyrimidin-2...) Show SMILES O=C(N1CCNCC1)c1ccc2c(c1)N(CC21CC1)c1ncc(cn1)-c1ccccc1 Show InChI InChI=1S/C25H25N5O/c31-23(29-12-10-26-11-13-29)19-6-7-21-22(14-19)30(17-25(21)8-9-25)24-27-15-20(16-28-24)18-4-2-1-3-5-18/h1-7,14-16,26H,8-13,17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GRUENENTHAL GMBH US Patent					Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...				US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4
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