Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM354665'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM354665 (US9809582, Example 24 | US9809582, Example 25 | US...) Show SMILES COc1ccc(cc1OC)[C@H](Cc1c(Cl)c[n+]([O-])cc1Cl)OC(=O)c1ccc(CNCC(C)(C(=O)OC2CCN(C)CC2)c2ccccc2)s1 |r| Show InChI InChI=1S/C37H41Cl2N3O7S/c1-37(25-8-6-5-7-9-25,36(44)48-26-14-16-41(2)17-15-26)23-40-20-27-11-13-34(50-27)35(43)49-32(19-28-29(38)21-42(45)22-30(28)39)24-10-12-31(46-3)33(18-24)47-4/h5-13,18,21-22,26,32,40H,14-17,19-20,23H2,1-4H3/t32-,37?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
CHIESI FARMACEUTICI S.p.A. US Patent					Assay Description PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...				US Patent US9809582 (2017) BindingDB Entry DOI: 10.7270/Q2H1345N
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM354665 (US9809582, Example 24 | US9809582, Example 25 | US...) Show SMILES COc1ccc(cc1OC)[C@H](Cc1c(Cl)c[n+]([O-])cc1Cl)OC(=O)c1ccc(CNCC(C)(C(=O)OC2CCN(C)CC2)c2ccccc2)s1 |r| Show InChI InChI=1S/C37H41Cl2N3O7S/c1-37(25-8-6-5-7-9-25,36(44)48-26-14-16-41(2)17-15-26)23-40-20-27-11-13-34(50-27)35(43)49-32(19-28-29(38)21-42(45)22-30(28)39)24-10-12-31(46-3)33(18-24)47-4/h5-13,18,21-22,26,32,40H,14-17,19-20,23H2,1-4H3/t32-,37?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
CHIESI FARMACEUTICI S.p.A. US Patent					Assay Description PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...				US Patent US9809582 (2017) BindingDB Entry DOI: 10.7270/Q2H1345N
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM354665 (US9809582, Example 24 | US9809582, Example 25 | US...) Show SMILES COc1ccc(cc1OC)[C@H](Cc1c(Cl)c[n+]([O-])cc1Cl)OC(=O)c1ccc(CNCC(C)(C(=O)OC2CCN(C)CC2)c2ccccc2)s1 |r| Show InChI InChI=1S/C37H41Cl2N3O7S/c1-37(25-8-6-5-7-9-25,36(44)48-26-14-16-41(2)17-15-26)23-40-20-27-11-13-34(50-27)35(43)49-32(19-28-29(38)21-42(45)22-30(28)39)24-10-12-31(46-3)33(18-24)47-4/h5-13,18,21-22,26,32,40H,14-17,19-20,23H2,1-4H3/t32-,37?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
CHIESI FARMACEUTICI S.p.A. US Patent					Assay Description PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...				US Patent US9809582 (2017) BindingDB Entry DOI: 10.7270/Q2H1345N
					More data for this Ligand-Target Pair