Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM463564'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM463564 ((2S)-3-[(3S,4S)- 3-[(1R)-1- hdyroxyethyl]-4- (4-me...) Show SMILES COc1ccc(cc1OC1CN(C1)c1ccc(Cl)cn1)[C@@H]1CN(C[C@@]1(C)[C@@H](C)O)C(=O)[C@@H](O)CO |r| Show InChI InChI=1S/C25H32ClN3O6/c1-15(31)25(2)14-29(24(33)20(32)13-30)12-19(25)16-4-6-21(34-3)22(8-16)35-18-10-28(11-18)23-7-5-17(26)9-27-23/h4-9,15,18-20,30-32H,10-14H2,1-3H3/t15-,19+,20+,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description PDE4A, PDE4B, PDE4C, PDE4D, and PDE5 human recombinant proteins are expressed and purified from Saccharomyes cerevisiae that lack endogenous PDEs. T...				US Patent US10781202 (2020) BindingDB Entry DOI: 10.7270/Q2571G2N
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