Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50110035'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50110035 (1-[2-(3-Cyclopropylmethoxy-4-methoxy-phenyl)-propy...) Show SMILES COc1ccc(cc1OCC1CC1)C(C)Cn1ccnc1NC#N Show InChI InChI=1S/C18H22N4O2/c1-13(10-22-8-7-20-18(22)21-12-19)15-5-6-16(23-2)17(9-15)24-11-14-3-4-14/h5-9,13-14H,3-4,10-11H2,1-2H3,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag Curated by ChEMBL					Assay Description Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytes				Bioorg Med Chem Lett 12: 653-8 (2002) BindingDB Entry DOI: 10.7270/Q2DV1KF6
					More data for this Ligand-Target Pair