Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50110047'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50110047 (1-[1-(3-Cyclopentyloxy-4-difluoromethoxy-phenyl)-c...) Show SMILES FC(F)Oc1ccc(cc1OC1CCCC1)C1(Cn2cc[nH]c2=O)CC1 Show InChI InChI=1S/C19H22F2N2O3/c20-17(21)26-15-6-5-13(11-16(15)25-14-3-1-2-4-14)19(7-8-19)12-23-10-9-22-18(23)24/h5-6,9-11,14,17H,1-4,7-8,12H2,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag Curated by ChEMBL					Assay Description Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytes				Bioorg Med Chem Lett 12: 653-8 (2002) BindingDB Entry DOI: 10.7270/Q2DV1KF6
					More data for this Ligand-Target Pair