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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50110051'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50110051
PNG
(1-{2-[4-Methoxy-3-(5-phenyl-pentyloxy)-phenyl]-pro...)
Show SMILES COc1ccc(cc1OCCCCCc1ccccc1)C(C)Cn1ccnc1NC#N
Show InChI InChI=1S/C25H30N4O2/c1-20(18-29-15-14-27-25(29)28-19-26)22-12-13-23(30-2)24(17-22)31-16-8-4-7-11-21-9-5-3-6-10-21/h3,5-6,9-10,12-15,17,20H,4,7-8,11,16,18H2,1-2H3,(H,27,28)
PDB

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 36n/an/an/an/an/an/a



Janssen-Cilag

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytes

Bioorg Med Chem Lett 12: 653-8 (2002)


BindingDB Entry DOI: 10.7270/Q2DV1KF6
More data for this
Ligand-Target Pair