Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50231324'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50231324 (CHEMBL4098616) Show SMILES COc1cccc(c1)-c1nc(co1)C(=O)n1nc(C)cc1C Show InChI InChI=1S/C16H15N3O3/c1-10-7-11(2)19(18-10)16(20)14-9-22-15(17-14)12-5-4-6-13(8-12)21-3/h4-9H,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
South China Agricultural University Curated by ChEMBL					Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 mins				Bioorg Med Chem 25: 1852-1859 (2017) Article DOI: 10.1016/j.bmc.2017.01.047 BindingDB Entry DOI: 10.7270/Q2MG7RS3
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