new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50314563'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))
BDBM50314563
PNG
(3-(1-(3-(4-(pyrimidin-2-yl)piperazin-1-yl)propylam...)
Show SMILES N#Cc1cccc(c1)-c1nnc(NCCCN2CCN(CC2)c2ncccn2)c2cc3ccccn3c12
Show InChI InChI=1S/C28H27N9/c29-20-21-6-3-7-22(18-21)25-26-24(19-23-8-1-2-13-37(23)26)27(34-33-25)30-11-5-12-35-14-16-36(17-15-35)28-31-9-4-10-32-28/h1-4,6-10,13,18-19H,5,11-12,14-17H2,(H,30,34)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.03E+3n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation counting


Bioorg Med Chem Lett 20: 2163-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.044
BindingDB Entry DOI: 10.7270/Q2NK3F54
More data for this
Ligand-Target Pair