Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50328114'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50328114 (2,2-Dimethyl-5-morpholin-4-yl-N-(2-piperidin-1-yle...) Show SMILES CC1(C)Cc2c(CO1)c(nc1sc3c(NCCN4CCCCC4)ncnc3c21)N1CCOCC1 Show InChI InChI=1S/C25H34N6O2S/c1-25(2)14-17-18(15-33-25)23(31-10-12-32-13-11-31)29-24-19(17)20-21(34-24)22(28-16-27-20)26-6-9-30-7-4-3-5-8-30/h16H,3-15H2,1-2H3,(H,26,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	284	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of PDE4B1 expressed in yeast				J Med Chem 53: 6912-22 (2010) Article DOI: 10.1021/jm100524j BindingDB Entry DOI: 10.7270/Q2J966K2
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