Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50346095'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50346095 (4-(5-benzyl-6-methyl-2-phenylpyrimidin-4-ylamino)b...) Show SMILES Cc1nc(nc(Nc2ccc(cc2)C(O)=O)c1Cc1ccccc1)-c1ccccc1 Show InChI InChI=1S/C25H21N3O2/c1-17-22(16-18-8-4-2-5-9-18)24(27-21-14-12-20(13-15-21)25(29)30)28-23(26-17)19-10-6-3-7-11-19/h2-15H,16H2,1H3,(H,29,30)(H,26,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Asahi Kasei Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substrates				Bioorg Med Chem Lett 19: 3174-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.121 BindingDB Entry DOI: 10.7270/Q26110NQ
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