Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50455388'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50455388 (CHEMBL4205250) Show SMILES COc1ccc(cc1O)C(=O)N1CCc2cc(OC)c(OC3CCCC3)cc2C1 Show InChI InChI=1S/C23H27NO5/c1-27-20-8-7-16(11-19(20)25)23(26)24-10-9-15-12-21(28-2)22(13-17(15)14-24)29-18-5-3-4-6-18/h7-8,11-13,18,25H,3-6,9-10,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
South China Agricultural University Curated by ChEMBL					Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 mins				Bioorg Med Chem Lett 28: 1188-1193 (2018) Article DOI: 10.1016/j.bmcl.2018.02.056 BindingDB Entry DOI: 10.7270/Q2W66PBS
					More data for this Ligand-Target Pair