Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50466924'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50466924 (CHEMBL4285675) Show SMILES Cc1cc(C)n(n1)C(=O)c1ccc(o1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H13ClN2O2/c1-10-9-11(2)19(18-10)16(20)15-8-7-14(21-15)12-3-5-13(17)6-4-12/h3-9H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
South China Agricultural University Curated by ChEMBL					Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate measured after 30 mins				Bioorg Med Chem Lett 28: 3276-3280 (2018) Article DOI: 10.1016/j.bmcl.2018.03.031 BindingDB Entry DOI: 10.7270/Q23X89B3
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