Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50466945'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50466945 (CHEMBL4176569) Show SMILES Fc1ccc(-c2ccc(o2)C(=O)N2CCc3ccccc3C2)c(F)c1 Show InChI InChI=1S/C20H15F2NO2/c21-15-5-6-16(17(22)11-15)18-7-8-19(25-18)20(24)23-10-9-13-3-1-2-4-14(13)12-23/h1-8,11H,9-10,12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
South China Agricultural University Curated by ChEMBL					Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 mins				Bioorg Med Chem Lett 28: 3271-3275 (2018) Article DOI: 10.1016/j.bmcl.2018.04.068 BindingDB Entry DOI: 10.7270/Q2057JMP
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