Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50493948'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50493948 (CHEMBL2442462) Show SMILES CC(C)(C)CNC(=O)Cc1ccc(Nc2nc(ncc2C(N)=O)N2CCCC2)cc1 Show InChI InChI=1S/C22H30N6O2/c1-22(2,3)14-25-18(29)12-15-6-8-16(9-7-15)26-20-17(19(23)30)13-24-21(27-20)28-10-4-5-11-28/h6-9,13H,4-5,10-12,14H2,1-3H3,(H2,23,30)(H,25,29)(H,24,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description Inhibition of recombinant human PDE4B using cAMP as substrate after 30 mins				Bioorg Med Chem 21: 7025-37 (2013) Article DOI: 10.1016/j.bmc.2013.09.013 BindingDB Entry DOI: 10.7270/Q2DZ0C84
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