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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50523325'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))
BDBM50523325
PNG
(CHEMBL4541773)
Show SMILES COc1ccc(CNc2cccnc2)cc1-c1cccc(F)c1
Show InChI InChI=1S/C19H17FN2O/c1-23-19-8-7-14(12-22-17-6-3-9-21-13-17)10-18(19)15-4-2-5-16(20)11-15/h2-11,13,22H,12H2,1H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 340n/an/an/an/an/an/a



Southern Medical University

Curated by ChEMBL


Assay Description
Inhibition of human full length N-terminal GST-tagged PDE4B1 expressed in baculovirus infected Sf9 cells using cAMP as substrate incubated for 1 hr b...


Eur J Med Chem 168: 221-231 (2019)


Article DOI: 10.1016/j.ejmech.2019.02.026
BindingDB Entry DOI: 10.7270/Q28W3HQT
More data for this
Ligand-Target Pair