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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50525005'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50525005
PNG
(CHEMBL4459298 | US11401286, Example 171)
Show SMILES CCc1cc(Nc2ccc(CC(N)=O)cc2)nc(n1)-c1cccc(Cl)c1
Show InChI InChI=1S/C20H19ClN4O/c1-2-16-12-19(23-17-8-6-13(7-9-17)10-18(22)26)25-20(24-16)14-4-3-5-15(21)11-14/h3-9,11-12H,2,10H2,1H3,(H2,22,26)(H,23,24,25)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 43n/an/an/an/an/an/a



Tetra Discovery Partners, Inc.

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...

J Med Chem 62: 4884-4901 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00193
BindingDB Entry DOI: 10.7270/Q26H4MVT
More data for this
Ligand-Target Pair