Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cAMP-specific 3',5'-cyclic phosphodiesterase 4C (Rattus norvegicus) | BDBM50010981 ((Ro 20-1724)4-(3-Butoxy-4-methoxy-benzyl)-imidazol...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of cAMP-specific calcium-independent phosphodiesterase (IPDE) | J Med Chem 34: 291-8 (1991) BindingDB Entry DOI: 10.7270/Q2NV9MG8 | |||||||||||
More data for this Ligand-Target Pair |