Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50240404 ((Ibudilast)1-(2-Isopropyl-pyrazolo[1,5-a]pyridin-3...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents | DrugBank Article PubMed | n/a | n/a | 166 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human PDE4D expressed in insect sf9 cells using [3H]-cAMP as substrate | Citation and Details Article DOI: 10.1021/acs.jmedchem.9b02170 BindingDB Entry DOI: 10.7270/Q2W95DVV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50240404 ((Ibudilast)1-(2-Isopropyl-pyrazolo[1,5-a]pyridin-3...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents | DrugBank Article PubMed | n/a | n/a | 166 | n/a | n/a | n/a | n/a | n/a | n/a |
Matrix Laboratories Limited Curated by ChEMBL | Assay Description Inhibition of human PDE4D | J Med Chem 51: 5471-89 (2008) Article DOI: 10.1021/jm800582j BindingDB Entry DOI: 10.7270/Q2GQ6ZNK | |||||||||||
More data for this Ligand-Target Pair |