Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4D' and Ligand = 'BDBM50304418'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50304418 (CHEMBL596394 | cis-4-(3,4-Dimethoxyphenyl)-2-[3-(m...) Show SMILES COc1ccc(cc1OC)C1=NN(Cc2cccc(CN3CCOCC3)c2)C(=O)[C@@H]2CC=CC[C@H]12 |r,c:34,t:11| Show InChI InChI=1S/C28H33N3O4/c1-33-25-11-10-22(17-26(25)34-2)27-23-8-3-4-9-24(23)28(32)31(29-27)19-21-7-5-6-20(16-21)18-30-12-14-35-15-13-30/h3-7,10-11,16-17,23-24H,8-9,12-15,18-19H2,1-2H3/t23-,24+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 601-8550 Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysis				Bioorg Med Chem 17: 6959-70 (2009) Article DOI: 10.1016/j.bmc.2009.08.014 BindingDB Entry DOI: 10.7270/Q2WH2Q26
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