Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4D' and Ligand = 'BDBM50353706'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50353706 (CHEMBL1828652) Show SMILES CC(C)Nc1nc2oc3c(NCc4cccnc4)ncnc3c2c2CC(C)(C)CCc12 Show InChI InChI=1S/C24H28N6O/c1-14(2)29-21-16-7-8-24(3,4)10-17(16)18-19-20(31-23(18)30-21)22(28-13-27-19)26-12-15-6-5-9-25-11-15/h5-6,9,11,13-14H,7-8,10,12H2,1-4H3,(H,29,30)(H,26,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of human PDE4D3 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assay				Eur J Med Chem 46: 4946-56 (2011) Article DOI: 10.1016/j.ejmech.2011.07.054 BindingDB Entry DOI: 10.7270/Q2VM4CPM
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